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SIM_3D Super Resolution Microscope
Super-Resolution, High Quality, Fast Imaging
The application of structural illumination microscopy enhances the super resolution microscope beyond the optical diffraction limitation. The x, y axis resolution reaches 165 nm, and the z axis resolution reaches 352 nm. The performance is two times higher than conventional optical microscopes. Building with the image algorithm technology/software developed by Enli Tech, the noise of non-focal plane can be accurately eliminated and the high resolution three-dimensional diagram is produced. This is the best solution with high cost/profit ratio for three-dimensional structure measurement.
| 3D Super Resolution Microscope | Specifications |
|---|---|
| iSIM-3DF |
a. 3D fluorescent slice image acquisition b. Surface topography analysis and 3-dimensional image display |
| SRM Model |
The algorithm for Super resolution fluorescence |
| Super Resolution Structured Illuminator | Specifications |
|---|---|
| Optical Transmission |
360 nm to 800 nm |
| Light Source |
425 nm to 650 nm Peaks: 450/25 nm, 550/40 nm, 630/20 nm |
| Extinction ratio |
> 1500:1 |
| Maximum Frame Rate @ 8bit |
120 FPS (frame/sec) |
| Minimum exposure time @ 8bit |
8.3 ms |
| Input trigger / Output trigger |
TTL, BNC connector |
| Output trigger delay |
User Programmable (ms) |
Beyond the optical diffraction limitation. Twice the resolution of conventional optical microscopes
Enli Tech SIM 3D Super Resolution Microscope is designed in accordance with the technology of Structured Illumination Microscopy. Through the method of projecting the light pattern onto the focal plane and the build-in image algorithm technology/software, the signal of focal plane is acquired and the noise of the non-focal plane is eliminated. We successfully break through the optical diffraction limitation and the performance of Enli Tech’s 3D Super Resolution Microscope is two times higher than the conventional optical microscopes.
▲Optical section fluorescent images of bovine pulmonary artery endothelial cells
Fast imaging. The Time Resolution of 0.2 sec/frame
Enli Tech SIM 3D Super Resolution Microscope is equipped with high-speed image capturing performance. The frame rate is 5 fps (frames per second). In other words, every image can be acquired in 0.2 second. The high-speed image capturing performance satisfies the needs of bio-related research.
Z-axis high resolution 3D fluorescence imaging technology
Enli Tech SIM3D Super Resolution Microscope offers the following two types to display high-resolution fluorescent images:
● Optical Slice Image
● 3D Stack Image
▲3D stack fluorescent image of microtubules
Upgrading microscope, Integrating SIM system, Providing total solutions
Enli Tech suggests and customizes different alternatives for customers in accordance with their needs：
● Enli Tech SIM total solution：providing SIM total solution including hardware, software, installation and training.
● Upgrading Microscopes solution：we can also offer the selective modularized solution. For example, if you have the optical microscope already, we can integrate the super resolution structural illuminator into your system and upgrade it to 3D super resolution microscope.
To satisfy user’s need for measuring three-dimensional micro-structures, Enli Tech 3D Super Resolution Microscope uses iSIM-3DF and SRM Model algorithm and integrates spatial-temporal control of the super-resolution structure light source, and a high-speed nano-shift-control system to upgrade the super-resolution structural light source to super resolution microscope. Enli Tech 3D Super Resolution Microscope can be used in the following fields:
◆ Biotechnology: Bio and medical applications
- Research of stem cell and
cancer cell (Three-dimensional structure)
- Research of chemical and physical stimulate/treatment of cancer
- Research of cancer cell transfer/inhibit
- Research of heredity and gene
- Precision Medical
